SCHEMBL7588385

SCHEMBL7588385

O=C(OC12CCCCC1O2)c1ccc(Cl)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
SMN1; SMN2 Q16637 4/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNA5 P30532 1/20 0.39
CHRNA7 P36544 1/20 0.39
CHRNA4 P43681 1/20 0.39
GLA P06280 1/20 0.38
CYP2C19 P33261 2/20 0.37
LMNA P02545 1/20 0.37
CYP2D6 P10635 1/20 0.37
GAA P10253 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
EPHX1 P07099 2/20 0.37
KMT2A Q03164 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7610955 0.87 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2CYP2C19GAAEPHX1
SCHEMBL6903507 0.87 KMT2A (0.40) ALDH1A1CHRNA7CYP2C19LMNACYP2D6
SCHEMBL6905915 0.87 KMT2A (0.40) ALDH1A1CHRNA7CYP2C19LMNACYP2D6
SCHEMBL6907956 0.87 KMT2A (0.40) ALDH1A1CHRNA7CYP2C19LMNACYP2D6
SCHEMBL7597793 0.86 POLB (0.41) ALDH1A1CHRNA7CYP2C19LMNACYP2D6
SCHEMBL7639019 0.86 POLB (0.41) ALDH1A1CHRNA7CYP2C19LMNACYP2D6
SCHEMBL7630204 0.83 PTPN2 (0.44) ALDH1A1SMN1; SMN2L3MBTL1EPHX1KMT2A
SCHEMBL7596827 0.82 LMNA (0.39) CHRNB2CHRNA5CHRNA7CHRNA4LMNA
SCHEMBL7597063 0.79 MEN1 (0.38) ALDH1A1SMN1; SMN2CYP2C19LMNACYP2D6
SCHEMBL7597565 0.78 SMN1; SMN2 (0.45) ALDH1A1SMN1; SMN2L3MBTL1CYP2C19LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6384265-B1 ACID CATALYSIS FOR REARRANGEMENT/INVERSION OF STEREOCONFIGURATION; KINETIC RESOLUTION OF RACEMIC MIXTURES USING A CHIRAL CATALYST COLORADO STATE UNIVERSITY RESEARCH FOUNDATION 2002-05-07 US disclosed
EP-1169291-A1 METHODS FOR PRODUCING $g(a)-ACYLOXY CARBONYL COMPOUNDS FROM ENOL ESTER EPOXIDES COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2002-01-09 EP disclosed
WO-2000056696-A1 METHODS FOR PRODUCING α-ACYLOXY CARBONYL COMPOUNDS FROM ENOL ESTER EPOXIDES COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2000-09-28 WO disclosed