SCHEMBL7597063

SCHEMBL7597063

Cc1cc(C)cc(C(=O)OC23CCCCC2O3)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
KMT2A Q03164 1/20 0.38
HTR3E A5X5Y0 1/20 0.38
NR1I2 O75469 1/20 0.38
HTR3B O95264 1/20 0.38
HTR3A P46098 1/20 0.38
HTR3D Q70Z44 1/20 0.38
HTR3C Q8WXA8 1/20 0.38
TAS1R3 Q7RTX0 1/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
TAS1R2 Q8TE23 1/20 0.37
NPSR1 Q6W5P4 3/20 0.34
LMNA P02545 1/20 0.34
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7597565 0.87 SMN1; SMN2 (0.45) CYP2C19KMT2ANPSR1LMNAALDH1A1
SCHEMBL7610955 0.86 ALDH1A1 (0.41) CYP1A2CYP2C19KMT2AALDH1A1NPC1
SCHEMBL6903507 0.80 KMT2A (0.40) MEN1CYP1A2CYP2D6CYP2C19KMT2A
SCHEMBL6907956 0.80 KMT2A (0.40) MEN1CYP1A2CYP2D6CYP2C19KMT2A
SCHEMBL6905915 0.80 KMT2A (0.40) MEN1CYP1A2CYP2D6CYP2C19KMT2A
SCHEMBL7639019 0.79 POLB (0.41) MEN1CYP1A2CYP2D6CYP2C19KMT2A
SCHEMBL7597793 0.79 POLB (0.41) MEN1CYP1A2CYP2D6CYP2C19KMT2A
SCHEMBL7588385 0.79 ALDH1A1 (0.40) CYP2D6CYP2C19KMT2ANPSR1LMNA
SCHEMBL7594315 0.77 EPHX1 (0.36) TAS1R3TAS1R1TAS1R2LMNANPC1
SCHEMBL7596827 0.75 LMNA (0.39) MEN1CYP1A2CYP2D6KMT2AHTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6384265-B1 ACID CATALYSIS FOR REARRANGEMENT/INVERSION OF STEREOCONFIGURATION; KINETIC RESOLUTION OF RACEMIC MIXTURES USING A CHIRAL CATALYST COLORADO STATE UNIVERSITY RESEARCH FOUNDATION 2002-05-07 US disclosed
EP-1169291-A1 METHODS FOR PRODUCING $g(a)-ACYLOXY CARBONYL COMPOUNDS FROM ENOL ESTER EPOXIDES COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2002-01-09 EP disclosed
WO-2000056696-A1 METHODS FOR PRODUCING α-ACYLOXY CARBONYL COMPOUNDS FROM ENOL ESTER EPOXIDES COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2000-09-28 WO disclosed