Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597063 | 0.87 | MEN1 (0.38) | SMN1; SMN2NPSR1NPC1RAB9AALDH1A1 | |
| SCHEMBL7610955 | 0.84 | ALDH1A1 (0.41) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL6905915 | 0.84 | KMT2A (0.40) | NPSR1ALDH1A1LMNACYP2C19POLB | |
| SCHEMBL6903507 | 0.84 | KMT2A (0.40) | NPSR1ALDH1A1LMNACYP2C19POLB | |
| SCHEMBL6907956 | 0.84 | KMT2A (0.40) | NPSR1ALDH1A1LMNACYP2C19POLB | |
| SCHEMBL7597793 | 0.83 | POLB (0.41) | NPSR1ALDH1A1LMNACYP2C19POLB | |
| SCHEMBL7639019 | 0.83 | POLB (0.41) | NPSR1ALDH1A1LMNACYP2C19POLB | |
| SCHEMBL7594315 | 0.81 | EPHX1 (0.36) | NPC1RAB9ALMNAHDAC4CASP8 | |
| SCHEMBL7596827 | 0.80 | LMNA (0.39) | NPSR1LMNAPOLBKMT2A | |
| SCHEMBL7588385 | 0.78 | ALDH1A1 (0.40) | SMN1; SMN2NPSR1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384265-B1 | ACID CATALYSIS FOR REARRANGEMENT/INVERSION OF STEREOCONFIGURATION; KINETIC RESOLUTION OF RACEMIC MIXTURES USING A CHIRAL CATALYST | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION | 2002-05-07 | — | — | US | disclosed |
| EP-1169291-A1 | METHODS FOR PRODUCING $g(a)-ACYLOXY CARBONYL COMPOUNDS FROM ENOL ESTER EPOXIDES | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000056696-A1 | METHODS FOR PRODUCING α-ACYLOXY CARBONYL COMPOUNDS FROM ENOL ESTER EPOXIDES | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2000-09-28 | — | — | WO | disclosed |