Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7580836 | 0.90 | EDNRA (0.44) | EDNRAEDNRB | |
| SCHEMBL7991567 | 0.87 | EDNRA (0.62) | EDNRAEDNRB | |
| SCHEMBL7591710 | 0.86 | EDNRA (0.56) | EDNRAEDNRB | |
| SCHEMBL8395334 | 0.85 | LMNA (0.37) | EDNRAEDNRB | |
| SCHEMBL7852059 | 0.82 | EDNRA (0.65) | EDNRAEDNRB | |
| SCHEMBL7585609 | 0.79 | EDNRB (0.51) | EDNRAEDNRB | |
| SCHEMBL8399581 | 0.76 | EDNRA (0.44) | EDNRAEDNRB | |
| SCHEMBL7591508 | 0.76 | EDNRA (0.54) | EDNRAEDNRB | |
| SCHEMBL7589698 | 0.76 | ALDH1A1 (0.47) | — | |
| SCHEMBL6973178 | 0.75 | EDNRA (0.51) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768304-B1 | N-(Pyrimidinyl)-benzenesulfonamides as medicaments | HOFFMANN LA ROCHE (CH) | 2002-05-22 | — | — | EP | disclosed |
| EP-0768304-A1 | N-(Pyrimidinyl)-benzenesulfonamides as medicaments | F. HOFFMANN-LA ROCHE AG (CH) | 1997-04-16 | — | — | EP | disclosed |