Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.32 |
| ▸ | GCLC | P48506 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10724598 | 0.85 | GSR (0.50) | GABRR1PMP22CPB2GSRRNPEP | |
| SCHEMBL10693782 | 0.82 | GABRR1 (0.38) | GABRR1PMP22GABBR2GABBR1 | |
| SCHEMBL1119747 | 0.79 | GABRR1 (0.44) | GABRR1PMP22CPB2GSRRNPEP | |
| SCHEMBL325264 | 0.79 | CYP1A2 (0.50) | GSR | |
| SCHEMBL28224631 | 0.79 | HDAC1 (0.48) | PMP22CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL2567543 | 0.76 | CA2 (0.48) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL29029474 | 0.73 | PMP22 (0.35) | PMP22GCLCCHRM1AKR1A1CHRM3 | |
| SCHEMBL5761 | 0.73 | PMP22 (0.35) | PMP22GCLCCHRM1AKR1A1CHRM3 | |
| SCHEMBL27809644 | 0.72 | GABRR1 (0.48) | GABRR1PMP22GSRRNPEPGABBR2 | |
| SCHEMBL9567295 | 0.72 | GPR84 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |
| WO-2002100416-A1 | SOCS-5 MOLECULES, SCREENING THEREFORE AND THERAPEUTIC USES THEREOF | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2002-12-19 | — | — | WO | disclosed |