SCHEMBL7590844

SCHEMBL7590844

[CH2]CCCCSc1cccc(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.38
ALDH1A1 P00352 5/20 0.35
LMNA P02545 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
MAPK1 P28482 2/20 0.34
IDO1 P14902 2/20 0.34
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
DRD3 P35462 1/20 0.34
DHFR P00374 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
HPGD P15428 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5168941 0.91 ACHE (0.46) ACHEALDH1A1LMNAKMT2AMAPT
SCHEMBL7595204 0.87 ACHE (0.42) ACHEALDH1A1KMT2AMAOAMAOB
SCHEMBL30753697 0.82 ALDH1A1 (0.50) ACHEALDH1A1KMT2AMAPTHTT
SCHEMBL425169 0.81 MAOA (0.45) ACHEALDH1A1LMNAKMT2AMAPT
SCHEMBL21102039 0.80 HDAC1 (0.38) ACHEALDH1A1KMT2AMAPTHTT
SCHEMBL17277459 0.80 TAAR1 (0.44) ACHEALDH1A1LMNAKMT2AMAPT
SCHEMBL12460455 0.78 IGF1R (0.44) LMNAKMT2AMAPTHTTMEN1
SCHEMBL10144174 0.77 ACHE (0.44) ACHEALDH1A1KMT2AMAOAMAOB
SCHEMBL17277336 0.77 KIF11 (0.49) ACHEALDH1A1MAPTMAOAMAOB
SCHEMBL12460462 0.77 IGF1R (0.42) KMT2AMEN1POLBDRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0844269-B1 BLOCK COPOLYMER HAVING FUNCTIONAL GROUPS AT BOTH ENDS KATAOKA KAZUNORI (JP) 2002-10-23 EP disclosed
US-5929177-A LIVING POLYMER WITH HYDROPHILIC, HYDROPHOBIC SEGMENTS Kataoka, Kazunori (JP) 1999-07-27 US disclosed
EP-0844269-A1 BLOCK POLYMER HAVING FUNCTIONAL GROUPS AT BOTH ENDS Kataoka, Kazunori (JP) 1998-05-27 EP disclosed