Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.49 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570857 | 0.88 | CCR2 (0.56) | CCR2POLBKCNH2KDM4EPIK3CD | |
| SCHEMBL7593952 | 0.86 | AVPR2 (0.56) | — | |
| SCHEMBL17609451 | 0.84 | PTK2B (0.55) | CCR2POLBBRD4 | |
| SCHEMBL7571678 | 0.82 | KCNH2 (0.63) | CCR2POLBKCNH2KDM4EACLY | |
| SCHEMBL7596259 | 0.79 | CCR2 (0.50) | CCR2POLBKCNH2PIK3CDPTGES2 | |
| SCHEMBL30925543 | 0.79 | SLC40A1 (0.78) | — | |
| SCHEMBL27214315 | 0.79 | SLC40A1 (0.78) | — | |
| SCHEMBL3560058 | 0.78 | SLC16A3 (0.58) | CCR2KCNH2KDM4E | |
| SCHEMBL6717132 | 0.78 | ACLY (0.54) | CCR2POLBPTGES2BRD4ACLY | |
| SCHEMBL3019464 | 0.78 | CCR2 (0.59) | CCR2POLBKCNH2PIK3CDPTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |