Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.50 |
| ▸ | ACLY | P53396 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571634 | 0.83 | SLC22A12 (0.53) | CCR2KCNH2SLC22A12POLBPIK3CA | |
| SCHEMBL7591202 | 0.79 | CCR2 (0.60) | CCR2ACLYKCNH2POLBPTGES2 | |
| SCHEMBL7595509 | 0.78 | SLC22A12 (0.56) | ACLYSLC22A12PTGES2 | |
| SCHEMBL7591642 | 0.77 | ACLY (0.48) | CCR2ACLYSLC22A12PTGES2BRD4 | |
| SCHEMBL16592647 | 0.77 | ATIC (0.56) | ACLYSLC22A12 | |
| SCHEMBL9534684 | 0.76 | PTGS2 (0.54) | SLC22A12PTGES2TBXA2R | |
| SCHEMBL7570857 | 0.75 | CCR2 (0.56) | CCR2KCNH2POLBPTGES2PIK3CD | |
| SCHEMBL17240373 | 0.73 | SLC22A12 (0.52) | ACLYSLC22A12PTGES2TBXA2R | |
| SCHEMBL11945262 | 0.73 | TRPV4 (0.43) | CCR2ACLYSLC22A12TBXA2R | |
| SCHEMBL21569546 | 0.73 | PIK3CA (0.42) | ACLYSLC22A12POLBPIK3CAPTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |