Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 9/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 9/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTAFR | P25105 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6942480 | 0.85 | PTAFR (0.39) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL6944366 | 0.76 | HTR1A (0.38) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL7595261 | 0.75 | HTR1A (0.53) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL8710411 | 0.74 | HTR6 (0.51) | HTR1AADRA1DADRA1AADRA1BPTGES | |
| SCHEMBL15922822 | 0.74 | HTR1A (0.65) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL6943758 | 0.73 | PTAFR (0.60) | PTAFR | |
| SCHEMBL6943291 | 0.73 | PTAFR (0.53) | MAPTPTAFR | |
| SCHEMBL8369436 | 0.71 | MAPT (0.49) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL28744247 | 0.70 | F2 (0.48) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL4164605 | 0.70 | MAPT (0.55) | HTR1AMAPTMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020128491-A1 | Method for synthesizing diaryl-substituted heterocyclic compounds, including tetrahydrofurans | RAO ALLA VENKATA RAMA (IN) | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128491-A1 | Method for synthesizing diaryl-substituted heterocyclic compounds, including tetrahydrofurans | TPMT, TPI1, GTF2I | HTR1A 751/4885ADRA1D 4212/4885ADRA1A 3966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.