Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.60 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.47 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18653823 | 0.89 | MAPT (0.62) | MAPTNPSR1PKMPOLBALDH3A1 | |
| SCHEMBL11629310 | 0.88 | ALDH3A1 (0.76) | MAPTNPSR1PKMPOLBALDH3A1 | |
| SCHEMBL5841267 | 0.87 | PKM (0.60) | MAPTNPSR1PKMPOLBALDH3A1 | |
| SCHEMBL11686855 | 0.87 | CA1 (0.64) | MAPTNPSR1PKMPOLBALDH3A1 | |
| SCHEMBL11323706 | 0.86 | ALDH3A1 (0.81) | MAPTNPSR1PKMPOLBALDH3A1 | |
| SCHEMBL5786327 | 0.83 | KMT2A (0.78) | MAPTNPSR1PKMPOLBALDH3A1 | |
| SCHEMBL10502186 | 0.83 | HCAR3 (0.58) | MAPTPKMPOLBALDH3A1CASP6 | |
| SCHEMBL7813230 | 0.82 | CASP6 (0.57) | MAPTNPSR1PKMPOLBALDH3A1 | |
| SCHEMBL2282371 | 0.81 | MAPT (0.68) | MAPTNPSR1PKMPOLBALDH3A1 | |
| SCHEMBL1532370 | 0.80 | MAPT (0.66) | MAPTNPSR1PKMPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780376-B1 | 2-Acylamino-9-aryl-acridines, process for their preparation, and light-sensitive compositions containing them | AGFA GEVAERT (BE) | 2002-10-16 | — | — | EP | disclosed |
| US-4207261-A | Process for preparing o-phenylenediamine | MAGYAR ASVANYOLAJ ES FOLDGAZ KISERLETI INTEZET (HU) | 1980-06-10 | — | — | US | disclosed |