SCHEMBL9185447

SCHEMBL9185447

O=C(O)c1ccc(S(=O)(=O)O)c([N+](=O)[O-])c1

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 1/20 0.64
POLB P06746 1/20 0.63
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
TSHR P16473 2/20 0.58
LMNA P02545 1/20 0.58
HCAR3 P49019 11/20 0.58
VCAM1 P19320 1/20 0.52
APEX1 P27695 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28909765 0.98 POLB (0.62) CASP6POLBMEN1KMT2ATSHR
SCHEMBL7591997 0.87 CASP6 (0.64) CASP6POLBMEN1KMT2ATSHR
SCHEMBL20572634 0.85 POLB (0.62) CASP6POLBMEN1KMT2ATSHR
SCHEMBL3530451 0.85 VCAM1 (0.71) CASP6POLBMEN1KMT2ATSHR
SCHEMBL6003204 0.85 POLB (0.62) CASP6POLBMEN1KMT2ATSHR
SCHEMBL9183692 0.85 POLB (0.62) CASP6POLBMEN1KMT2ATSHR
SCHEMBL9658195 0.83 POLB (0.56) CASP6POLBMEN1KMT2ATSHR
SCHEMBL9499862 0.83 POLB (0.59) CASP6POLBMEN1KMT2ATSHR
SCHEMBL19071961 0.81 VCAM1 (0.79) POLBLMNAVCAM1
SCHEMBL9658192 0.80 POLB (0.56) CASP6POLBMEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3408257-B1 LINKER MOLECULE AND USE OF IT IN PROCESS FOR PURIFICATION OF PEPTIDES Belyntic GmbH (DE) 2021-12-22 EP disclosed
EP-3408257-A1 LINKER MOLECULE AND USE THEREOF IN METHODS FOR PURIFYING PEPTIDES Belyntic GmbH (DE) 2018-12-05 EP disclosed
US-20170283787-A1 METHOD FOR NON-ENZYMATIC COMBINATION OF NUCLEIC ACID CHAINS JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2017-10-05 US disclosed
WO-2017129818-A1 LINKER MOLECULE AND USE THEREOF IN METHODS FOR PURIFYING PEPTIDES HUMBOLDT-UNIVERSITÄT ZU BERLIN (DE) 2017-08-03 WO disclosed
EP-3187584-A1 METHOD FOR NON-ENZYMATIC COMBINATION OF NUCLEIC ACID CHAINS Japan Science and Technology Agency (JP) 2017-07-05 EP disclosed
US-5378704-A Non-peptidic angiotensin-II-receptor-antagonists E. R. SQUIBB & SONS, INC. (US) 1995-01-03 US disclosed
US-4029643-A Chromium containing azo dyes NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1977-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170283787-A1 METHOD FOR NON-ENZYMATIC COMBINATION OF NUCLEIC ACID CHAINS RNGTT, POLRMT, DNTT CASP6 2066/4885POLB 8/4885MEN1 4389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.