Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17907433 | 0.92 | ALDH1A1 (0.48) | LMNAMAPTHTTHPGDESR1 | |
| SCHEMBL1128694 | 0.85 | LMNA (0.44) | LMNAMAPTHPGDESR1ESR2 | |
| SCHEMBL8065192 | 0.84 | ALDH1A1 (0.56) | LMNAMAPTHTTHPGDSRD5A2 | |
| SCHEMBL699850 | 0.78 | LMNA (1.00) | LMNAMAPTHTTHPGDESR1 | |
| SCHEMBL18423 | 0.78 | LMNA (1.00) | LMNAMAPTHTTHPGDESR1 | |
| SCHEMBL7940723 | 0.77 | MEN1 (0.63) | LMNAMAPTHTTHPGDESR1 | |
| SCHEMBL3644304 | 0.77 | TSHR (0.55) | HPGDSRD5A2SMN1; SMN2CA1CA2 | |
| SCHEMBL31256698 | 0.77 | MAPK1 (0.47) | LMNAMAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL3974617 | 0.75 | PARP10 (0.47) | LMNAMAPTKMT2ACA1CA2 | |
| SCHEMBL8068752 | 0.75 | ALDH1A1 (0.45) | LMNACA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090017-B1 | NOVEL COMPOUNDS DERIVED FROM ALPHA-D-XYLOSE, PREPARATION METHOD AND THERAPEUTIC USE | FOURNIER IND & SANTE (FR) | 2002-10-30 | — | — | EP | disclosed |
| US-6291433-B1 | Derivatives of α-D-Thioxyloside and their use against atheroma | FOURNIER INDUSTRIE ET SANTE (FR) | 2001-09-18 | — | — | US | disclosed |
| EP-1090017-A1 | NOVEL COMPOUNDS DERIVED FROM $g(a)-D-XYLOSE, PREPARATION METHOD AND THERAPEUTIC USE | FOURNIER INDUSTRIE ET SANTE (FR) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067261-A1 | NOVEL COMPOUNDS DERIVED FROM α-D-XYLOSE, PREPARATION METHOD AND THERAPEUTIC USE | FOURNIER INDUSTRIE ET SANTE (FR) | 1999-12-29 | — | — | WO | disclosed |