SCHEMBL7592364

SCHEMBL7592364

C[C@H](NCC(=O)OC(C)(C)CN[C@@H](COCc1ccccc1)C(=O)O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.50
PPARG P37231 1/20 0.46
MME P08473 1/20 0.43
FOLH1 Q04609 1/20 0.43
CTSS P25774 2/20 0.43
MMP9 P14780 1/20 0.40
MMP14 P50281 1/20 0.40
KLK7 P49862 2/20 0.37
KLK5 Q9Y337 2/20 0.37
REN P00797 1/20 0.37
SLC1A1 P43005 1/20 0.37
RAB9A P51151 1/20 0.36
CA1 P00915 1/20 0.35
CTSL P07711 1/20 0.35
CTSK P43235 1/20 0.35
PTPN2 P17706 2/20 0.34
PTPN1 P18031 2/20 0.34
CDC25B P30305 2/20 0.34
PTPN6 P29350 1/20 0.34
CDC25A P30304 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6706558 0.83 PPARA (0.55) PPARAPPARGMMEFOLH1CTSS
SCHEMBL6318413 0.83 PPARA (0.63) PPARAPPARGMMEFOLH1CTSS
SCHEMBL1414344 0.83 PPARA (0.63) PPARAPPARGMMEFOLH1CTSS
SCHEMBL4863387 0.83 PPARA (0.63) PPARAPPARGMMEFOLH1CTSS
SCHEMBL5230870 0.79 PPARA (0.56) PPARAPPARGMMEFOLH1CTSS
SCHEMBL7588488 0.75 FOLH1 (0.59) PPARAPPARGMMEFOLH1CTSS
SCHEMBL31163762 0.75 PPARA (0.66) PPARAPPARGMMEFOLH1CTSS
SCHEMBL27586123 0.75 PPARA (0.66) PPARAPPARGMMEFOLH1CTSS
SCHEMBL8070441 0.75 PPARA (0.56) PPARAPPARGFOLH1CTSSMMP9
SCHEMBL1414515 0.74 PPARA (0.55) PPARAPPARGFOLH1CTSSMMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020042415-A1 Dipeptide derivatives CARPINO PHILIP ALBERT (US) 2002-04-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020042415-A1 Dipeptide derivatives GIPR, GHRHR, GHSR PPARA 1854/4885PPARG 426/4885MME 2553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.