Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | GPR17 | Q13304 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696076 | 0.79 | LMNA (0.53) | HSD17B10KEAP1GPR17LMNAFFAR1 | |
| SCHEMBL7592100 | 0.72 | — | — | |
| SCHEMBL8095483 | 0.69 | CYP1A2 (0.50) | HSD17B10GPR17LMNACHRM1TBXA2R | |
| SCHEMBL7595517 | 0.68 | ALDH1A1 (0.39) | HSD17B10LMNACHRM1TBXA2RPDE4A | |
| SCHEMBL4157307 | 0.65 | KEAP1 (0.39) | HSD17B10KEAP1LMNAFFAR1CYP1A2 | |
| SCHEMBL9637092 | 0.65 | GPR17 (0.57) | KEAP1GPR17FFAR1HIF1ANPSR1 | |
| SCHEMBL621486 | 0.64 | TPMT (0.33) | LMNACYP1A2KDM4E | |
| SCHEMBL9563941 | 0.64 | POLB (0.35) | HSD17B10LMNACYP1A2CYP2C9KDM4E | |
| SCHEMBL28830916 | 0.64 | NPSR1 (0.50) | HSD17B10KEAP1GPR17LMNAFFAR1 | |
| Hydrochloric Acid SCHEMBL9169414 | 0.62 | KEAP1 (0.37) | KEAP1LMNAFFAR1CYP1A2ALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |
| US-6310243-B1 | BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY | NYCOMED IMAGING AS (NO) | 2001-10-30 | — | — | US | disclosed |
| US-5993780-A | A POLYIODOARYLALKYL ALCOHOL OR DERIVATIVE | NYCOMED IMAGING AS (NO) | 1999-11-30 | — | — | US | disclosed |
| US-5882628-A | Contrast media | NYCOMED IMAGING AS (NO) | 1999-03-16 | — | — | US | disclosed |
| EP-0782564-A1 | IODINATED X-RAY CONTRAST MEDIA | NYCOMED IMAGING AS (NO) | 1997-07-09 | — | — | EP | disclosed |
| WO-1996009282-A1 | IODINATED X-RAY CONTRAST MEDIA | NYCOMED IMAGING A/S (NO) | 1996-03-28 | — | — | WO | disclosed |