SCHEMBL7593034

SCHEMBL7593034

C1=CC2NN/C=C\c3ccccc3C2C=C1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL560766 0.83 HTR2A (0.32) HTR2A
SCHEMBL5698322 0.65 HTR2A (0.44) HTR2A
SCHEMBL15704498 0.63 HSPA1A (0.38)
SCHEMBL454276 0.63 HSPA1A (0.38)
SCHEMBL19004692 0.63 HSPA1A (0.38)
SCHEMBL363573 0.62 HTR2A (0.32) HTR2A
SCHEMBL972340 0.62 HTR2A (0.32) HTR2A
SCHEMBL5667976 0.62 HTR2A (0.32) HTR2A
SCHEMBL11507457 0.61 CASP3 (0.34)
SCHEMBL17792652 0.61 MEN1 (0.32) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002083629-A1 BISSULFONAMIDE DERIVATIVES AS INHIBITORS OF DEHYDROQUINATE SYNTHETASES AND TYPE II DEHYDROQUINASES ARROW THERAPEUTICS LIMITED (GB) 2002-10-24 WO disclosed
EP-1239852-A2 BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS Arrow Therapeutics Limited (GB) 2002-09-18 EP disclosed
WO-2001028537-A2 BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS ARROW THERAPEUTICS LIMITED (GB) 2001-04-26 WO disclosed