Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.35 |
| ▸ | GOT1 | P17174 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086196 | 0.80 | KCNQ2 (0.42) | KCNQ2MEN1KMT2AGAAHPGD | |
| SCHEMBL5866892 | 0.74 | KCNQ2 (0.41) | KCNQ2MEN1KMT2AGAAHPGD | |
| SCHEMBL5866890 | 0.74 | KCNQ2 (0.41) | KCNQ2MEN1KMT2AGAAHPGD | |
| SCHEMBL5866894 | 0.72 | IDO1 (0.46) | KCNQ2MEN1KMT2AGAAHPGD | |
| SCHEMBL7588273 | 0.67 | THRB (0.42) | MEN1KMT2ASMN1; SMN2HTR3EHTR3B | |
| SCHEMBL7586241 | 0.60 | HTR3E (0.40) | MEN1KMT2AALDH1A1HTR3EHTR3B | |
| SCHEMBL6086523 | 0.60 | HTR3E (0.42) | KMT2ASMN1; SMN2ALDH1A1HSD17B10HTR3E | |
| SCHEMBL20887127 | 0.60 | PRKDC (0.54) | MEN1KMT2AGAAALDH1A1HSD17B10 | |
| SCHEMBL7585802 | 0.58 | LMNA (0.51) | MEN1KMT2AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL14693884 | 0.58 | IDO1 (0.53) | MEN1KMT2AALDH1A1PKMHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246795-A2 | ANTIBACTERIAL AGENTS | Tularik Inc. (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001051456-A2 | ANTIBACTERIAL AGENTS | TULARIK INC. (US) | 2001-07-19 | — | — | WO | disclosed |