Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7586241 | 0.82 | HTR3E (0.40) | KMT2AALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL7582051 | 0.79 | GPR35 (0.41) | LMNARECQLKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL7591071 | 0.78 | MAOB (0.47) | RAB9ANPC1KDM4ECA2 | |
| SCHEMBL6777820 | 0.77 | KEAP1 (0.40) | LMNAKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6086196 | 0.76 | KCNQ2 (0.42) | LMNAKMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7585739 | 0.75 | ADORA3 (0.49) | LMNARECQLKMT2AALDH1A1RAB9A | |
| SCHEMBL6086523 | 0.75 | HTR3E (0.42) | KMT2AALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7701242 | 0.73 | ALDH1A1 (0.73) | LMNARECQLKMT2AALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL7709305 | 0.72 | ALDH1A1 (0.71) | LMNARECQLKMT2AALDH1A1RAB9A | |
| SCHEMBL5935550 | 0.71 | HTT (0.53) | LMNARECQLKMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246795-A2 | ANTIBACTERIAL AGENTS | Tularik Inc. (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001051456-A2 | ANTIBACTERIAL AGENTS | TULARIK INC. (US) | 2001-07-19 | — | — | WO | disclosed |