Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.40 |
| ▸ | HTR3B | O95264 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CBR1 | P16152 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7585802 | 0.82 | LMNA (0.51) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL6086523 | 0.81 | HTR3E (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6086196 | 0.79 | KCNQ2 (0.42) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL7582051 | 0.79 | GPR35 (0.41) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL6777820 | 0.78 | KEAP1 (0.40) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7591071 | 0.74 | MAOB (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7586299 | 0.72 | GPR35 (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7588263 | 0.72 | POLB (0.53) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL7588083 | 0.71 | BCAT1 (0.45) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5867078 | 0.69 | CBR1 (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246795-A2 | ANTIBACTERIAL AGENTS | Tularik Inc. (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001051456-A2 | ANTIBACTERIAL AGENTS | TULARIK INC. (US) | 2001-07-19 | — | — | WO | disclosed |