Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5870715 | 0.82 | DRD3 (0.52) | LMNAKMT2ADRD3MAPTCCR2 | |
| SCHEMBL5870720 | 0.80 | LTA4H (0.52) | ALDH1A1POLBLMNAKMT2ADRD3 | |
| SCHEMBL5870727 | 0.77 | DRD3 (0.51) | DRD3LTA4HEPHX2CCR2 | |
| SCHEMBL12384539 | 0.77 | SLC6A3 (0.56) | DRD3DRD2SIGMAR1 | |
| SCHEMBL5870879 | 0.75 | DRD3 (0.77) | POLBKMT2ADRD3GAACCR2 | |
| SCHEMBL3116231 | 0.75 | SIGMAR1 (0.56) | ALDH1A1POLBLMNAKMT2AMAPT | |
| SCHEMBL5276400 | 0.73 | EPHX2 (0.59) | EPHX2HTR1ADRD2SIGMAR1 | |
| SCHEMBL12538069 | 0.72 | CCR2 (0.79) | MAPTCCR2 | |
| SCHEMBL1943094 | 0.72 | CCR2 (0.79) | MAPTCCR2 | |
| SCHEMBL2559828 | 0.72 | KMT2A (0.64) | ALDH1A1POLBLMNAKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002069895-A2 | HETEROCYCLIC ANALGESIC COMPOUNDS AND METHODS OF USE THEREOF | SEPRACOR, INC. (US) | 2002-09-12 | — | — | WO | disclosed |