Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA5A | P35218 | 2/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL2892185 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL28500032 | 0.89 | — | — | |
| SCHEMBL583553 | 0.89 | — | — | |
| SCHEMBL28271386 | 0.85 | SLC34A1 (0.50) | SLC34A1KDM4ECYP2C19KMT2ALMNA | |
| Phosphoric Acid SCHEMBL4931344 | 0.85 | SLC34A1 (0.50) | SLC34A1KDM4ECYP2C19KMT2ALMNA | |
| Fluoride Ion SCHEMBL1708173 | 0.85 | — | — | |
| SCHEMBL29167943 | 0.85 | SLC34A1 (0.50) | SLC34A1KDM4ECYP2C19KMT2ALMNA | |
| Ammonia Solution, Strong SCHEMBL1289336 | 0.85 | — | — | |
| SCHEMBL28492233 | 0.81 | SLC34A1 (0.47) | SLC34A1KDM4ECYP2C19KMT2ALMNA | |
| Ammonia Solution, Strong SCHEMBL6562014 | 0.81 | SLC34A1 (0.47) | SLC34A1KDM4ECYP2C19KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252118-A1 | POTASSIUM MONOFLUOROPHOSPHATE AS A CORROSION INHIBITOR | DOMTAR INC. (CA) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001055052-A1 | POTASSIUM MONOFLUOROPHOSPHATE AS A CORROSION INHIBITOR | DOMTAR INC. (CA) | 2001-08-02 | — | — | WO | disclosed |