Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668593 | 0.78 | PTGS1 (0.41) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL14651687 | 0.76 | TRPA1 (0.67) | TRPA1SLC6A4HDAC3HDAC4HDAC1 | |
| SCHEMBL933056 | 0.72 | — | — | |
| SCHEMBL84504 | 0.72 | — | — | |
| SCHEMBL29624242 | 0.72 | TRPA1 (0.48) | TRPA1SLC6A4LMNAHDAC3HDAC4 | |
| SCHEMBL13863427 | 0.71 | LMNA (0.45) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| 2,2'-Dithiodiethanesulfonic Acid SCHEMBL773704 | 0.71 | PTGS1 (0.45) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL8460647 | 0.70 | — | — | |
| 2,2'-Dithiodiethanesulfonic Acid SCHEMBL8403166 | 0.69 | PTGS1 (0.43) | PTGS1PDE4ALMNASLC6A6CYP2C19 | |
| SCHEMBL11604930 | 0.69 | TRPA1 (0.57) | TRPA1SLC6A4HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998057538-A1 | COMPLETE ACTIVATION OF MAMMALIAN OOCYTES | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1998-12-23 | — | — | WO | claimed |
| US-12527305-B2 | Porcine reproductive and respiratory syndrome virus resistant animals | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2026-01-20 | — | — | US | disclosed |
| US-10676538-B2 | Inhibitors of Staphylococcus pseudintermedius sortase | KANIA STEPHEN ANTHONY (US) | 2020-06-09 | — | — | US | disclosed |
| US-20190241675-A1 | Inhibitors of Staphylococcus pseudintermedius Sortase | BEMIS DAVID (US) | 2019-08-08 | — | — | US | disclosed |
| EP-2167531-B1 | STREPTOCOCCUS PNEUMONIAE PILUS ANTIGENS | NOVARTIS AG (CH) | 2012-03-21 | — | — | EP | disclosed |
| US-20110275132-A1 | PURIFICATION OF BACTERIAL ANTIGENS | NOVARTIS AG (CH) | 2011-11-10 | — | — | US | disclosed |
| US-20110097360-A1 | STREPTOCOCCUS PNEUMONIAE PILUS ANTIGENS | NOVARTIS AG (CH) | 2011-04-28 | — | — | US | disclosed |
| US-7829117-B2 | Compounds and methods for reducing undesired toxicity of chemotherapeutic agents | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-7829540-B2 | Compounds and methods for reducing undesired toxicity of chemotherapeutic agents | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-7829539-B2 | Heteroconjugated disulfides of 2-mercaptoethane sulfonate sodium | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-20050272677-A1 | Delivery of a substance to a pre-determined site | APPLIED NANOSYSTEMS B.V. (NL) | 2005-12-08 | — | — | US | disclosed |
| EP-1490028-A1 | DELIVERY OF A SUBSTANCE TO A PRE-DETERMINED SITE | Applied NanoSystems B.V. (NL) | 2004-12-29 | — | — | EP | disclosed |
| EP-1397123-A2 | DELIVERY OF SMALL HYDROPHILIC MOLECULES PACKAGED INTO LIPID VESICLES | Applied NanoSystems B.V. (NL) | 2004-03-17 | — | — | EP | disclosed |
| WO-2003084508-A1 | DELIVERY OF A SUBSTANCE TO A PRE-DETERMINED SITE | APPLIED NANOSYSTEMS B.V. (NL) | 2003-10-16 | — | — | WO | disclosed |
| EP-1350507-A1 | Delivery of a substance to a pre-determinated site | Applied NanoSystems B.V. (NL) | 2003-10-08 | — | — | EP | disclosed |
| US-20030118636-A1 | Delivery of small hydrophilic molecules packaged into lipid vesicles | APPLIED NANOSYSTEMS B.V. (NL) | 2003-06-26 | — | — | US | disclosed |
| WO-2003000233-A2 | DELIVERY OF SMALL HYDROPHILIC MOLECULES PACKAGED INTO LIPID VESICLES | APPLIED NANOSYSTEMS B.V. (NL) | 2003-01-03 | — | — | WO | disclosed |
| EP-1269993-A1 | Delivery of small hydrophilic molecules packaged into lipid vesicles | Applied NanoSystems B.V. (NL) | 2003-01-02 | — | — | EP | disclosed |
| US-20020128203-A1 | Methods of identifying inhibitory compounds and uses thereof | UNIVERSITE DE LAUSANNE (CH) | 2002-09-12 | — | — | US | disclosed |
| WO-2002024177-A2 | METHODS OF IDENTIFYING INHIBITORY COMPOUNDS AND USES THEREOF | UNIVERSITY OF LAUSANNE (CH) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030118636-A1 | Delivery of small hydrophilic molecules packaged into lipid vesicles | CHMP4B, SCAMP2, SLC47A2 | TRPA1 457/4885SLC6A4 1001/4885PTGS1 2147/4885 |
| US-20050272677-A1 | Delivery of a substance to a pre-determined site | TACR1, TACR2, NPSR1 | TRPA1 1907/4885SLC6A4 56/4885PTGS1 749/4885 |
| US-12527305-B2 | Porcine reproductive and respiratory syndrome virus resistant animals | PIGS, ZFR, ZP1 | TRPA1 3005/4885SLC6A4 1397/4885PTGS1 4522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.