Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7645402 | 0.84 | CYP19A1 (0.34) | NQO2CYP19A1KDM4ELMNASOST | |
| SCHEMBL7592864 | 0.82 | NQO2 (0.38) | NQO2CYP19A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5385291 | 0.81 | CYP3A4 (0.41) | NQO2CYP19A1SOSTSMN1; SMN2GSK3B | |
| SCHEMBL7594461 | 0.80 | RAB9A (0.40) | NQO2CYP19A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL14337819 | 0.80 | POLB (0.39) | SMN1; SMN2TARBP2GSK3BMEN1KMT2A | |
| SCHEMBL7594183 | 0.78 | HSP90AA1 (0.37) | NQO2CYP19A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7642818 | 0.76 | ALDH1A1 (0.34) | NQO2CYP19A1LMNASMN1; SMN2MAPT | |
| SCHEMBL5385211 | 0.76 | CYP3A4 (0.45) | SMN1; SMN2TARBP2GSK3BMEN1KMT2A | |
| SCHEMBL14337947 | 0.75 | CYP3A4 (0.30) | — | |
| SCHEMBL14337881 | 0.75 | CYP3A4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850945-B1 | Chiral diphosphine compound, intermediate for preparing the same, transition metal complex having the same diphosphine compound as ligand and asymmetric hydrogenation catalyst | TAKASAGO PERFUMERY CO LTD (JP) | 2002-11-27 | — | — | EP | disclosed |
| EP-0850945-A1 | Chiral diphosphine compound, intermediate for preparing the same, transition metal complex having the same diphosphine compound as ligand and asymmetric hydrogenation catalyst | Takasago International Corporation (JP) | 1998-07-01 | — | — | EP | disclosed |