Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321843 | 0.88 | NPC1 (0.38) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7592864 | 0.87 | NQO2 (0.38) | HSP90AA1HSP90AB1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL7599038 | 0.85 | NPC1 (0.37) | HSP90AA1HSP90AB1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL7592861 | 0.84 | NPC1 (0.37) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7598402 | 0.84 | ALDH1A1 (0.35) | HSP90AA1MAPTSMN1; SMN2ALDH1A1NQO2 | |
| SCHEMBL7594461 | 0.84 | RAB9A (0.40) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7594464 | 0.78 | NQO2 (0.36) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL7642818 | 0.77 | ALDH1A1 (0.34) | HSP90AA1MAPTSMN1; SMN2ALDH1A1NQO2 | |
| SCHEMBL6319700 | 0.75 | NPC1 (0.35) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL5379348 | 0.74 | CYP3A4 (0.36) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850945-B1 | Chiral diphosphine compound, intermediate for preparing the same, transition metal complex having the same diphosphine compound as ligand and asymmetric hydrogenation catalyst | TAKASAGO PERFUMERY CO LTD (JP) | 2002-11-27 | — | — | EP | disclosed |
| EP-0850945-A1 | Chiral diphosphine compound, intermediate for preparing the same, transition metal complex having the same diphosphine compound as ligand and asymmetric hydrogenation catalyst | Takasago International Corporation (JP) | 1998-07-01 | — | — | EP | disclosed |