Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.34 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594464 | 0.84 | NQO2 (0.36) | CYP19A1NQO2LMNAKDM4ESOST | |
| SCHEMBL5384389 | 0.82 | CYP3A4 (0.39) | CYP19A1NQO2SOSTHTTRECQL | |
| SCHEMBL7642818 | 0.81 | ALDH1A1 (0.34) | CYP19A1NQO2LMNAHSP90AA1MAPT | |
| SCHEMBL7598402 | 0.77 | ALDH1A1 (0.35) | CYP19A1NQO2LMNAHSP90AA1MAPT | |
| SCHEMBL7594461 | 0.77 | RAB9A (0.40) | CYP19A1NQO2KDM4EMAPTNPC1 | |
| SCHEMBL7592864 | 0.77 | NQO2 (0.38) | CYP19A1NQO2LMNAKDM4EHSP90AA1 | |
| SCHEMBL5383846 | 0.75 | CYP3A4 (0.37) | POLB | |
| SCHEMBL6566586 | 0.74 | CYP19A1 (0.34) | CYP19A1NQO2LMNAKDM4ESOST | |
| SCHEMBL29565868 | 0.73 | CYP19A1 (0.36) | CYP19A1NQO2LMNAKDM4ESOST | |
| SCHEMBL28341 | 0.73 | CYP19A1 (0.36) | CYP19A1NQO2LMNAKDM4ESOST |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472539-B1 | BASIFICATION OF MONOMER WITH SUCH AS BUTYLLITHIUM THEN DIMERIZATION IN NONPOLAR SOLVENT CONTAINING SUSPENDED OXIDATIVE METAL SALT SUCH AS FERRIC CHLORIDE; HIGH YIELD; CHEMICAL INTERMEDIATE TO ASYMMETRIC SYNTHESIS CATALYST | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-10-29 | — | — | US | disclosed |