Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | CCR2 | P41597 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CCKBR | P32239 | 1/20 | 0.45 |
| ▸ | HK1 | P19367 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573964 | 0.85 | ALDH1A1 (0.65) | ALDH1A1CCR2PKMKDM4EMEN1 | |
| SCHEMBL7593916 | 0.81 | CCR2 (0.78) | ALDH1A1CCR2PKMKDM4EMEN1 | |
| SCHEMBL6553589 | 0.80 | MAPT (0.60) | ALDH1A1PKMMEN1KMT2AMAPT | |
| SCHEMBL6554533 | 0.80 | MAPT (0.60) | ALDH1A1PKMMEN1KMT2AMAPT | |
| SCHEMBL7593692 | 0.79 | ALDH1A1 (0.60) | ALDH1A1CCR2PKMKDM4EMEN1 | |
| SCHEMBL6554529 | 0.79 | MAPT (0.59) | ALDH1A1PKMMEN1KMT2AMAPT | |
| SCHEMBL7587888 | 0.79 | KEAP1 (0.54) | ALDH1A1KMT2AMAPTLMNAPOLB | |
| SCHEMBL323126 | 0.78 | VCAM1 (0.64) | ALDH1A1KMT2AMAPTMAPK1 | |
| SCHEMBL7573980 | 0.78 | KDM4E (0.63) | ALDH1A1CCR2PKMKDM4EMEN1 | |
| SCHEMBL7595588 | 0.77 | CCR2 (0.65) | ALDH1A1CCR2PKMKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |