Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977896 | 0.85 | TSHR (0.40) | CASP6G6PDCASP7MAPTALDH1A1 | |
| SCHEMBL3092968 | 0.84 | G6PD (0.50) | CASP6G6PDCASP7MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL28469617 | 0.83 | G6PD (0.49) | CASP6G6PDCASP7MAPTALDH1A1 | |
| SCHEMBL1567631 | 0.82 | MAPT (0.45) | MAPTALDH1A1POLBMEN1LMNA | |
| SCHEMBL2852455 | 0.80 | ALDH1A1 (0.53) | CASP6CASP7MAPTALDH1A1POLB | |
| SCHEMBL18280815 | 0.80 | TSHR (0.33) | ALDH1A1MAPK1GAACYP3A4KDM4E | |
| SCHEMBL2925692 | 0.77 | GABRP (0.50) | CASP6G6PDCASP7MAPTALDH1A1 | |
| SCHEMBL28896783 | 0.76 | SELL (0.48) | MAPTALDH1A1POLBMEN1LMNA | |
| SCHEMBL1349070 | 0.76 | GAA (0.39) | MAPTALDH1A1POLBKMT2ACYP1A2 | |
| SCHEMBL27835976 | 0.76 | CYP1A2 (0.37) | MAPTALDH1A1POLBKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841924-B1 | BENZIMIDAZOLE COMPOUNDS | UNIV NEWCASTLE VENTURES LTD (GB) | 2002-10-02 | — | — | EP | claimed |