Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UQCRB | P14927 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.46 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590886 | 0.86 | MEN1 (0.61) | UQCRBHSD17B2GAAMAPTMEN1 | |
| SCHEMBL7589388 | 0.80 | CCR2 (0.54) | HSD17B2GAAMEN1KMT2ATP53 | |
| SCHEMBL13028659 | 0.79 | KMT2A (0.67) | UQCRBALOX12ITGA1HSD17B2GAA | |
| SCHEMBL25212958 | 0.74 | PKM (0.74) | MAPTMEN1KMT2AARALDH1A1 | |
| SCHEMBL1857218 | 0.74 | KMT2A (0.74) | ALOX12ITGA1HSD17B2GAAMEN1 | |
| SCHEMBL7213023 | 0.73 | SLC10A6 (0.73) | ALOX12MAPTMEN1KMT2AHTT | |
| SCHEMBL7577405 | 0.73 | PTPRC (0.60) | ALOX12GAAMAPTMEN1KMT2A | |
| SCHEMBL23109349 | 0.73 | CA1 (0.65) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL812691 | 0.73 | POLB (0.67) | UQCRBMAPTMEN1KMT2AHTT | |
| SCHEMBL7577210 | 0.72 | HTT (0.62) | ITGA1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |