Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 4/20 | 0.40 |
| ▸ | KDR | P35968 | 4/20 | 0.40 |
| ▸ | KIF5B | P33176 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766729 | 0.86 | MEN1 (0.46) | PDGFRBPDGFRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7801874 | 0.85 | KDM4E (0.49) | PDGFRBPDGFRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7790969 | 0.84 | EGFR (0.55) | KDM4EALDH1A1SMN1; SMN2CSF1REGFR | |
| SCHEMBL360021 | 0.81 | EGFR (0.53) | PDGFRBPDGFRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7799373 | 0.79 | EGFR (0.44) | KDM4EALDH1A1SMN1; SMN2CSF1RRET | |
| SCHEMBL7797381 | 0.79 | KDM4E (0.43) | PDGFRBPDGFRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1539121 | 0.79 | RET (0.55) | KDM4EALDH1A1SMN1; SMN2RETKDR | |
| SCHEMBL1246693 | 0.78 | ABCG2 (0.58) | KDM4EALDH1A1SMN1; SMN2RETKDR | |
| SCHEMBL7797258 | 0.78 | KDR (0.59) | PDGFRBPDGFRAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7753469 | 0.78 | FGFR1 (0.56) | PDGFRBPDGFRARETKDRKIF5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002043735-A1 | INHIBITORS OF THROMBIN INDUCED PLATELET AGGREGATION | PARKER HUGHES INSTITUTE (US) | 2002-06-06 | — | — | WO | claimed |