Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17364455 | 0.82 | ALDH1A1 (0.50) | PDK2POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL27878252 | 0.81 | ESR1 (0.41) | PDK2POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL16425349 | 0.81 | MAPT (0.41) | PDK2POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL6577530 | 0.79 | GPR174 (0.47) | PDK2POLBMEN1KMT2ATSHR | |
| SCHEMBL7595576 | 0.79 | PDK2 (0.51) | PDK2POLBMEN1KMT2APPARD | |
| SCHEMBL13962705 | 0.79 | POLB (0.40) | PDK2POLBMEN1KMT2ATSHR | |
| SCHEMBL13962697 | 0.79 | POLB (0.40) | PDK2POLBMEN1KMT2ATSHR | |
| SCHEMBL16425350 | 0.79 | MEN1 (0.42) | PDK2POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL534499 | 0.79 | MAPT (0.39) | PDK2POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL2116437 | 0.78 | PTGS2 (0.66) | POLBMEN1KMT2AL3MBTL1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2684907-B1 | RESIN, OPTICAL MATERIAL, AND OPTICAL DEVICE | MITSUI CHEMICALS INC (JP) | 2020-02-26 | — | — | EP | disclosed |
| US-9221949-B2 | Resin, optical material, and optical device | MITSUI CHEMICALS, INC. (JP) | 2015-12-29 | — | — | US | disclosed |
| US-9221949-B2 | Resin, optical material, and optical device | MITSUI CHEMICALS, INC. (JP) | 2015-12-29 | — | — | US | disclosed |
| EP-2684907-A1 | RESIN, OPTICAL MATERIAL, AND OPTICAL DEVICE | Mitsui Chemicals, Inc. (JP) | 2014-01-15 | — | — | EP | disclosed |
| US-20020052354-A1 | Paramagnetic DOTA derivatives, pharmaceutical agents that contain the latter, process for their production, and their use for MR imaging of necrosis and infarction | SCHERING AG | 2002-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052354-A1 | Paramagnetic DOTA derivatives, pharmaceutical agents that contain the latter, process for their production, and their use for MR imaging of necrosis and infarction | TNNI3, NPR1, LPXN | PDK2 653/4885POLB 2148/4885MEN1 557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.