Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.35 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679914 | 1.00 | SLC9A1 (0.40) | SLC9A1HTR2AHTR2CHTR2BALDH1A1 | |
| Fumaric Acid SCHEMBL7591475 | 0.89 | SLC9A1 (0.39) | SLC9A1ALDH1A1MAPTHPGDTSHR | |
| Fumaric Acid SCHEMBL7679544 | 0.89 | SLC9A1 (0.39) | SLC9A1ALDH1A1MAPTHPGDTSHR | |
| Fumaric Acid SCHEMBL7679536 | 0.89 | SLC9A1 (0.39) | SLC9A1ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL6984509 | 0.83 | ALDH1A1 (0.41) | SLC9A1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL7677811 | 0.83 | ALDH1A1 (0.41) | SLC9A1HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL6984952 | 0.83 | ALDH1A1 (0.41) | SLC9A1HTR2AHTR2CHTR2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL7696213 | 0.82 | ALDH1A1 (0.40) | SLC9A1HTR2AHTR2CHTR2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL7594196 | 0.82 | ALDH1A1 (0.40) | SLC9A1HTR2AHTR2CHTR2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL7592478 | 0.82 | ALDH1A1 (0.40) | SLC9A1HTR2AHTR2CHTR2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451789-B1 | CENTRAL NERVOUS SYSTEM DISORDERS; COGNITION ACTIVATORS | LES LABORTOIRES SERVIER (FR) | 2002-09-17 | — | — | US | disclosed |
| US-20020042413-A1 | 1-aza-2-alkyl-6-aryl-cycloalkanes | RAULT SYLVAIN (FR) | 2002-04-11 | — | — | US | disclosed |
| US-6323222-B1 | COGNITION ACTIVATORS, ALZHEIMER*S DISEASE AND ENZYME INHIBITORS | ADIR ET COMPAGNIE (FR) | 2001-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020042413-A1 | 1-aza-2-alkyl-6-aryl-cycloalkanes | SULT2A1, GRIN2A, NR3C1 | SLC9A1 751/4885HTR2A 114/4885HTR2C 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.