Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 2/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 10/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8238063 | 0.88 | GHSR (0.51) | GHSRTACR1 | |
| SCHEMBL8564275 | 0.79 | CTSS (0.49) | PPARAGHSRCTSSPPARGKLK7 | |
| SCHEMBL8161727 | 0.77 | GHSR (0.39) | GHSRCTSSTACR1 | |
| SCHEMBL7979239 | 0.75 | GHSR (0.39) | PPARAGHSRPPARGTACR1 | |
| SCHEMBL8466975 | 0.75 | GHSR (0.39) | GHSRTACR1 | |
| SCHEMBL5247044 | 0.73 | PPARA (0.59) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL5247053 | 0.73 | PPARA (0.59) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL5247747 | 0.73 | PPARA (0.71) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL5227731 | 0.73 | PPARA (0.71) | PPARACTSSPPARGKLK7KLK5 | |
| SCHEMBL7511586 | 0.72 | PPARA (0.40) | PPARAGHSRCTSSPPARGKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994013696-A1 | SPIRO PIPERIDINES AND HOMOLOGS WHICH PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1994-06-23 | — | — | WO | disclosed |