Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8161727 | 0.89 | GHSR (0.39) | GHSRTACR1 | |
| SCHEMBL8466975 | 0.87 | GHSR (0.39) | GHSRTACR1 | |
| SCHEMBL8238063 | 0.86 | GHSR (0.51) | GHSRTACR1 | |
| Hydrochloric Acid SCHEMBL8606952 | 0.79 | GHSR (0.32) | GHSR | |
| SCHEMBL8462876 | 0.77 | GHSR (0.39) | GHSRACE | |
| SCHEMBL7595843 | 0.75 | PPARA (0.41) | GHSRPPARGPPARATACR1 | |
| SCHEMBL7930529 | 0.74 | GHSR (0.46) | GHSRACETACR1 | |
| Hydrochloric Acid SCHEMBL7575092 | 0.71 | GHSR (0.42) | GHSRACETACR1 | |
| SCHEMBL7848280 | 0.70 | GHSR (0.37) | GHSRACE | |
| SCHEMBL7381269 | 0.69 | GHSR (0.76) | GHSRTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228867-B1 | 2-PHENYL-PYRROLO(2,3-B)PYRIDINE DERIVATIVES FOR TREATING UROGENITAL AND SLEEP DISORDERS; ANTICARCINOGENIC AGENTS; BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2001-05-08 | — | — | US | disclosed |