Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 7/20 | 0.33 |
| ▸ | MMP1 | P03956 | 6/20 | 0.33 |
| ▸ | MMP9 | P14780 | 4/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8161727 | 0.95 | GHSR (0.39) | GHSRSLC6A2MMP12MMP13TACR1 | |
| SCHEMBL7979239 | 0.87 | GHSR (0.39) | GHSRTACR1 | |
| SCHEMBL8238063 | 0.86 | GHSR (0.51) | GHSRTACR1 | |
| SCHEMBL8462876 | 0.77 | GHSR (0.39) | GHSR | |
| SCHEMBL7595843 | 0.75 | PPARA (0.41) | GHSRTACR1 | |
| SCHEMBL7918487 | 0.74 | GHSR (0.43) | GHSRMMP3MMP1MMP9TACR1 | |
| SCHEMBL7930529 | 0.74 | GHSR (0.46) | GHSRMMP9TACR1MMP2 | |
| SCHEMBL8559971 | 0.73 | TACR1 (0.40) | MMP3TACR1 | |
| SCHEMBL9391707 | 0.72 | GHSR (0.36) | GHSRMMP3MMP1MMP9MMP2 | |
| SCHEMBL9395055 | 0.71 | MMP3 (0.36) | GHSRMMP3MMP1MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901489-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997044339-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1997-11-27 | — | — | WO | disclosed |