Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 3/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876795 | 0.89 | PARP1 (0.47) | SRD5A1PARP10PARP1MAPK14 | |
| SCHEMBL8877618 | 0.83 | SRD5A1 (0.42) | SRD5A1PARP10PARP1CYP19A1CYP11B1 | |
| SCHEMBL9591939 | 0.80 | PNMT (0.39) | — | |
| SCHEMBL9590810 | 0.80 | TYMS (0.34) | — | |
| SCHEMBL3372953 | 0.75 | SRD5A1 (0.54) | SRD5A1PARP10PARP1MAPK14CYP19A1 | |
| SCHEMBL8251126 | 0.69 | MAPK14 (0.55) | SRD5A1PARP10PARP1MAPK14 | |
| SCHEMBL6954820 | 0.67 | MAPK14 (0.65) | SRD5A1MAPK14 | |
| SCHEMBL29726050 | 0.66 | CASP1 (0.59) | SRD5A1CYP19A1CYP11B1CYP11B2GRM5 | |
| SCHEMBL192610 | 0.66 | CASP1 (0.59) | SRD5A1CYP19A1CYP11B1CYP11B2GRM5 | |
| SCHEMBL4184575 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151714-A1 | PROCESS FOR PREPARING 1,4-DISUBSTITUTED PIPERIDINE COMPOUNDS | CILAG AG (CH) | 2002-10-17 | — | — | US | disclosed |