Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | KDM4B | O94953 | 1/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10578361 | 0.86 | AURKA (0.55) | XDHSLC22A12CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL10580033 | 0.83 | SMN1; SMN2 (0.48) | XDHSLC22A12CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL10576818 | 0.81 | RXFP1 (0.53) | BCAT2LMNA | |
| SCHEMBL8443771 | 0.75 | KMO (0.49) | KMO | |
| SCHEMBL10579879 | 0.74 | XDH (0.44) | XDHSLC22A12P2RY14CSNK2A1BCAT2 | |
| SCHEMBL9749622 | 0.73 | ALOX5 (0.46) | XDHSLC22A12CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL10988314 | 0.73 | MEN1 (0.59) | KDM4AKDM4BKDM4DKDM4CP2RY14 | |
| SCHEMBL29279320 | 0.71 | PTPN1 (0.58) | KDM4AKDM4BKDM4DKDM4CKDM4E | |
| SCHEMBL22479801 | 0.71 | METAP2 (0.49) | XDHSLC22A12CSNK2A1CSNK2A2CSNK2B | |
| SCHEMBL10900757 | 0.70 | GRIN2D (0.53) | KDM4AKDM4BKDM4DKDM4CP2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690054-B1 | 1-Amino-2-cyclohexene derivatives and production process therefor | KURARAY CO (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5587486-A | CONDENSATION; CARBONYLATION; HYDROLYSIS; INTERMEDIATES IN THE PRODUCTION OF MEDICINAL AND AGRICULTURAL AGENTS | KURARAY CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0690054-A1 | 1-Amino-2-cyclohexene derivatives and production process therefor | KURARAY CO., LTD. (JP) | 1996-01-03 | — | — | EP | disclosed |
| US-4808599-A | IMMUNOMODULATORY, CARDIOTONIC AGENTS | RHONE-POULENC SANTE (FR) | 1989-02-28 | — | — | US | disclosed |