Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | F9 | P00740 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874491 | 0.87 | CNR2 (0.41) | ALOX5ADORA2ASLC9A1 | |
| SCHEMBL4315241 | 0.83 | ADRA2A (0.49) | ALOX5ADRA2AADRA2BF9PDPK1 | |
| SCHEMBL28744574 | 0.79 | ADRA2A (0.45) | ALOX5ADRA2AADRA2BF9BCAT2 | |
| SCHEMBL10944347 | 0.78 | ADRA2A (0.51) | ALOX5ADRA2AADRA2BF9ADORA2A | |
| SCHEMBL9825320 | 0.77 | SLC9A1 (0.38) | ALOX5ADRA2AADRA2BSLC9A1 | |
| SCHEMBL9825192 | 0.76 | KDM4E (0.39) | ALOX5XDHSLC22A12 | |
| SCHEMBL13129265 | 0.76 | ADRA2A (0.43) | ALOX5XDHSLC22A12ADRA2AADRA2B | |
| SCHEMBL8443771 | 0.75 | KMO (0.49) | ADRA2AADRA2B | |
| SCHEMBL7596515 | 0.73 | XDH (0.44) | ALOX5XDHSLC22A12CSNK2A2CSNK2B | |
| SCHEMBL21046206 | 0.73 | ADRA2A (0.41) | ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149819-A | Squarylium compounds and optical information recording medium using the same | RICOH COMPANY, LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| US-5085909-A | SQUARYLIUM COMPOUNDS AND OPTICAL INFORMATION RECORDING MEDIUM USING THE SAME | RICOH COMPANY, LTD. (JP) | 1992-02-04 | — | — | US | disclosed |
| US-5037575-A | Photostability | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0187015-B1 | SQUARILIUM COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | MITSUBISHI KASEI CORPORATION (JP) | 1991-05-29 | — | — | EP | disclosed |
| EP-0187015-A2 | Squarilium compound and liquid crystal composition containing the same | MITSUBISHI KASEI CORPORATION (JP) | 1986-07-09 | — | — | EP | disclosed |