Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796571 | 0.87 | HDAC4 (0.46) | MEN1MAPTKMT2AHDAC4HDAC7 | |
| Acridan SCHEMBL7793226 | 0.87 | HDAC4 (0.36) | MEN1MAPTKMT2AHDAC4HDAC7 | |
| Acridan SCHEMBL7755713 | 0.84 | HDAC4 (0.36) | MEN1MAPTKMT2AHDAC4HDAC7 | |
| Acridan SCHEMBL6586926 | 0.81 | ALDH1A1 (0.32) | MEN1MAPTKMT2AHDAC4HDAC7 | |
| SCHEMBL7787075 | 0.76 | MAPT (0.39) | MEN1MAPTKMT2AHDAC4HDAC7 | |
| Acridan SCHEMBL7594988 | 0.75 | HDAC3 (0.32) | HDAC4HDAC7HDAC5ALDH1A1TSHR | |
| SCHEMBL2218310 | 0.73 | HDAC4 (0.50) | MEN1MAPTKMT2AHDAC4HDAC7 | |
| Acridan SCHEMBL7755741 | 0.73 | HDAC4 (0.42) | MEN1KMT2AHDAC4HDAC7HDAC5 | |
| SCHEMBL7787066 | 0.72 | HDAC4 (0.44) | MEN1MAPTKMT2AHDAC4HDAC7 | |
| SCHEMBL5665141 | 0.72 | HDAC4 (0.44) | MEN1MAPTKMT2AHDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778946-B1 | NOVEL METHOD AND KITS FOR PRODUCING LIGHT FROM AN ACRIDAN COMPOUND | LUMIGEN INC (US) | 2002-10-23 | — | — | EP | disclosed |
| US-5723295-A | MULTISTAGE CHEMILUMINESCENT ASSAY WITH PEROXIDASE ENZYME, PH ADJUSTMENT | LUMIGEN, INC. (US) | 1998-03-03 | — | — | US | disclosed |
| US-5670644-A | CHEMILUMINESCENT REACTIONS, PEROXIDASE AND PH FOR IMMUNOASSAY | LUMIGEN, INC. (US) | 1997-09-23 | — | — | US | disclosed |