Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.31 |
| ▸ | BRD4 | O60885 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797026 | 0.90 | HDAC4 (0.38) | ALDH1A1TSHRHDAC4HDAC7HDAC5 | |
| Acridan SCHEMBL7594988 | 0.85 | HDAC3 (0.32) | ALDH1A1TSHRHDAC4HDAC7HDAC5 | |
| SCHEMBL7787075 | 0.83 | MAPT (0.39) | ALDH1A1TSHRHTR2AHTR2CHTR2B | |
| Acridan SCHEMBL7596523 | 0.81 | MEN1 (0.37) | ALDH1A1TSHRHTR2AHTR2CHTR2B | |
| Acridan SCHEMBL7793226 | 0.75 | HDAC4 (0.36) | ALDH1A1HDAC4HDAC7HDAC5BRD4 | |
| Acridan SCHEMBL6342017 | 0.74 | HDAC4 (0.38) | ALDH1A1TSHRHTR2AHTR2CHTR2B | |
| Acridan SCHEMBL7755713 | 0.72 | HDAC4 (0.36) | HTR2AHTR2CHTR2BHDAC4HDAC7 | |
| SCHEMBL8877458 | 0.72 | KDM4E (0.35) | ALDH1A1TSHRHDAC4HDAC7HDAC5 | |
| SCHEMBL7797048 | 0.72 | HDAC4 (0.39) | ALDH1A1HDAC4HDAC7HDAC5PIN1 | |
| Acridan SCHEMBL7755741 | 0.71 | HDAC4 (0.42) | HTR2AHTR2CHTR2BHDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778947-B1 | CHEMILUMINESCENT DETECTION OF HYDROLYTIC ENZYMES USING AN ACRIDAN | LUMIGEN INC (US) | 2004-05-12 | — | — | EP | claimed |
| EP-0778947-B1 | CHEMILUMINESCENT DETECTION OF HYDROLYTIC ENZYMES USING AN ACRIDAN | LUMIGEN INC (US) | 2004-05-12 | — | — | EP | disclosed |
| US-5686258-A | Chemiluminescent detection of hydrolytic enzymes using an acridan | LUMIGEN, INC. (US) | 1997-11-11 | — | — | US | disclosed |