Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 2/20 | 0.35 |
| ▸ | CCKBR | P32239 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797026 | 0.92 | HDAC4 (0.38) | MAPTMEN1KMT2AHDAC4HDAC7 | |
| SCHEMBL7796571 | 0.84 | HDAC4 (0.46) | MAPTMEN1KMT2AHDAC4HDAC7 | |
| Acridan SCHEMBL6586926 | 0.83 | ALDH1A1 (0.32) | MAPTMEN1KMT2AHDAC4HDAC7 | |
| SCHEMBL7793833 | 0.78 | HDAC4 (0.49) | MAPTHDAC4HDAC7HDAC5SMN1; SMN2 | |
| SCHEMBL6130200 | 0.77 | HDAC4 (0.46) | MAPTMEN1KMT2AHDAC4HDAC7 | |
| Acridan SCHEMBL7596523 | 0.76 | MEN1 (0.37) | MAPTMEN1KMT2AHDAC4HDAC7 | |
| SCHEMBL7797022 | 0.73 | HDAC4 (0.49) | MAPTMEN1KMT2AHDAC4HDAC7 | |
| SCHEMBL7787066 | 0.73 | HDAC4 (0.44) | MAPTMEN1KMT2AHDAC4HDAC7 | |
| SCHEMBL7787007 | 0.73 | MEN1 (0.41) | MAPTMEN1KMT2AHDAC4HDAC7 | |
| SCHEMBL7592240 | 0.72 | MAPT (0.41) | MAPTMEN1KMT2AHDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750748-B1 | NOVEL ARYL N-ALKYLACRIDANCARBOXYLATE DERIVATIVES USEFUL FOR CHEMILUMINESCENT DETECTION | LUMIGEN INC (US) | 2001-12-05 | — | — | EP | claimed |