SCHEMBL75968

SCHEMBL75968

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccc(N(c5ccc(-c6cccc7c6oc6ccccc67)cc5)c5ccc(-c6cccc7c6oc6ccccc67)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.55
GGPS1 O95749 1/20 0.43
PRKDC P78527 8/20 0.40
PTGES2 Q9H7Z7 1/20 0.40
CDC14B O60729 2/20 0.39
CDC14A Q9UNH5 2/20 0.39
MEN1 O00255 1/20 0.37
CSF1R P07333 1/20 0.37
PDGFRB P09619 1/20 0.37
MAPT P10636 1/20 0.37
KIT P10721 1/20 0.37
FLT3 P36888 1/20 0.37
KMT2A Q03164 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
PIK3CD O00329 4/20 0.36
PIK3CB P42338 4/20 0.36
PLA2G2A P14555 2/20 0.36
PLA2G4A P47712 2/20 0.36
PIK3CA P42336 3/20 0.36
PIK3CG P48736 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10109916 1.00 ALOX5 (0.55) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL6372603 1.00 ALOX5 (0.55) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL17705914 1.00 ALOX5 (0.55) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL6374224 1.00 ALOX5 (0.55) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL15496371 1.00 ALOX5 (0.55) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL25132623 1.00 ALOX5 (0.55) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL74451 1.00 ALOX5 (0.55) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL6373554 1.00 ALOX5 (0.55) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL21131445 1.00 ALOX5 (0.55) ALOX5GGPS1PRKDCPTGES2CDC14B
SCHEMBL15496182 1.00 ALOX5 (0.55) ALOX5GGPS1PRKDCPTGES2CDC14B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11751472-B2 Aromatic amine derivative and elecroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2023-09-05 US disclosed
US-11751472-B2 Aromatic amine derivative and elecroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2023-09-05 US disclosed
US-11538997-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2022-12-27 US disclosed
US-10446761-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2019-10-15 US disclosed
US-20190081245-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2019-03-14 US disclosed
US-20170294588-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2017-10-12 US disclosed
US-20170294588-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2017-10-12 US disclosed
US-20160351821-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-12-01 US disclosed
US-20160351821-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-12-01 US disclosed
US-9444053-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2016-09-13 US disclosed
US-20140159006-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-06-12 US disclosed
US-20140159006-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-06-12 US disclosed
US-8623522-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-01-07 US disclosed
US-8623522-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-01-07 US disclosed
US-20120181521-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed
US-20120181521-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 US disclosed
US-8129038-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-03-06 US disclosed
US-8129038-B2 Aromatic amine derivative and electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-03-06 US disclosed
US-20070278938-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-12-06 US disclosed
US-20070278938-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070278938-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME MAOA, SETD1A, EML4 ALOX5 3303/4885GGPS1 3690/4885PRKDC 2367/4885
US-10446761-B2 Aromatic amine derivative and electroluminescence device using the same EML4, DDC, TYR ALOX5 3471/4885GGPS1 3903/4885PRKDC 1880/4885
US-11751472-B2 Aromatic amine derivative and elecroluminescence device using the same ALK, ALKBH3, ACVRL1 ALOX5 1568/4885GGPS1 3715/4885PRKDC 2638/4885
US-20190081245-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME EML4, DDC, TYR ALOX5 3471/4885GGPS1 3903/4885PRKDC 1880/4885
US-20170294588-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME MAOA, SETD1A, EML4 ALOX5 3303/4885GGPS1 3690/4885PRKDC 2367/4885
US-20120181521-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME MAOA, SETD1A, EML4 ALOX5 3303/4885GGPS1 3690/4885PRKDC 2367/4885
US-11538997-B2 Aromatic amine derivative and electroluminescence device using the same EML4, DDC, TYR ALOX5 3471/4885GGPS1 3903/4885PRKDC 1880/4885
US-20160351821-A1 AROMATIC AMINE DERIVATIVE AND ELECTROLUMINESCENCE DEVICE USING THE SAME MAOA, SETD1A, EML4 ALOX5 3303/4885GGPS1 3690/4885PRKDC 2367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.