Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NPY4R | P50391 | 4/20 | 0.33 |
| ▸ | NPY1R | P25929 | 3/20 | 0.33 |
| ▸ | NPY2R | P49146 | 3/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600642 | 0.91 | ITGB3 (0.36) | CNR2CNR1ITGB3ITGA2BNPY4R | |
| SCHEMBL7595138 | 0.90 | CYP2C9 (0.44) | CNR2CNR1MDM2NPY4RNPY1R | |
| SCHEMBL7597057 | 0.89 | NPY4R (0.38) | CNR2CNR1MDM2NPY4RNPY1R | |
| SCHEMBL7595802 | 0.83 | TRPM8 (0.41) | CNR2CNR1NPY1R | |
| SCHEMBL7595142 | 0.83 | TRPM8 (0.41) | CNR2CNR1NPY1R | |
| SCHEMBL7600989 | 0.81 | NPY1R (0.41) | NPY4RNPY1RNPY5RMEN1KMT2A | |
| SCHEMBL7598351 | 0.81 | CNR1 (0.42) | CNR2CNR1NPY4RNPY1RNPY2R | |
| SCHEMBL7596200 | 0.81 | TRPM8 (0.37) | CNR2CNR1NPY1RRAB9ASMN1; SMN2 | |
| SCHEMBL28032819 | 0.81 | CNR1 (0.42) | CNR2CNR1NPY4RNPY1RNPY2R | |
| SCHEMBL1382274 | 0.81 | CNR1 (0.42) | CNR2CNR1NPY4RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | claimed |
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |