Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 6/20 | 0.41 |
| ▸ | NPY4R | P50391 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | MASP2 | O00187 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.35 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595138 | 0.92 | CYP2C9 (0.44) | NPY1RNPY4RNPY5RMEN1KMT2A | |
| SCHEMBL7595802 | 0.91 | TRPM8 (0.41) | NPY1RTRPM8 | |
| SCHEMBL7595142 | 0.91 | TRPM8 (0.41) | NPY1RTRPM8 | |
| SCHEMBL7600642 | 0.90 | ITGB3 (0.36) | NPY1RNPY4RNPY5RMEN1KMT2A | |
| SCHEMBL7598351 | 0.88 | CNR1 (0.42) | NPY1RNPY4RNPY5RTRPM8 | |
| SCHEMBL1382274 | 0.88 | CNR1 (0.42) | NPY1RNPY4RNPY5RTRPM8 | |
| SCHEMBL28032819 | 0.88 | CNR1 (0.42) | NPY1RNPY4RNPY5RTRPM8 | |
| SCHEMBL7596200 | 0.88 | TRPM8 (0.37) | NPY1RTRPM8 | |
| SCHEMBL7597379 | 0.87 | CNR1 (0.43) | MEN1KMT2ATRPM8 | |
| SCHEMBL7597777 | 0.87 | CNR1 (0.43) | MEN1KMT2ATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | claimed |
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |