Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596981 | 1.00 | TP53 (0.41) | TP53TSHRSMN1; SMN2KMT2ALMNA | |
| SCHEMBL23800877 | 0.91 | LMNA (0.34) | TP53SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL30175143 | 0.91 | LMNA (0.34) | TP53SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL7596077 | 0.90 | TSHR (0.36) | TP53TSHRSMN1; SMN2KMT2ALMNA | |
| SCHEMBL1332977 | 0.88 | MGLL (0.34) | TP53SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL1332545 | 0.87 | L3MBTL1 (0.35) | TP53SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL1332475 | 0.87 | L3MBTL1 (0.35) | TP53SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL1334130 | 0.87 | L3MBTL1 (0.35) | TP53SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL29565409 | 0.87 | L3MBTL1 (0.35) | TP53SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL29565416 | 0.87 | L3MBTL1 (0.35) | TP53SMN1; SMN2KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112264-B1 | POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2002-11-27 | — | — | EP | claimed |
| US-5961892-A | PHOTOCHROMIC | PPG INDUSTRIES OHIO, INC. (US) | 1999-10-05 | — | — | US | claimed |
| EP-1112264-B1 | POLYALKOXYLATED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2002-11-27 | — | — | EP | disclosed |
| US-5961892-A | PHOTOCHROMIC | PPG INDUSTRIES OHIO, INC. (US) | 1999-10-05 | — | — | US | disclosed |