SCHEMBL7597866

SCHEMBL7597866

O=S(=O)(Oc1cccc(C(F)(F)F)c1C(F)(F)F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 2/20 0.33
DRD2 P14416 3/20 0.33
HTR1D P28221 2/20 0.33
DRD3 P35462 2/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
CNR1 P21554 1/20 0.32
GPR183 P32249 1/20 0.32
CNR2 P34972 1/20 0.32
CES1 P23141 1/20 0.32
HSD11B1 P28845 2/20 0.31
NFE2L2 Q16236 2/20 0.31
MRGPRX4 Q96LA9 1/20 0.31
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7601041 0.90 DRD2 (0.39) SLC22A12DRD2HTR1DDRD3MRGPRX4
SCHEMBL7598091 0.81 KMT2A (0.36) SLC22A12MEN1KMT2ACES1HSD11B1
SCHEMBL15453472 0.80 HSD11B1 (0.36) SLC22A12MEN1KMT2ACNR1GPR183
SCHEMBL6550061 0.79 DRD2 (0.34) DRD2HTR1DDRD3
SCHEMBL15765781 0.79 CNR2 (0.38) SLC22A12MEN1KMT2ACNR1GPR183
SCHEMBL15453721 0.77 CNR2 (0.37) SLC22A12DRD2HTR1DDRD3MEN1
SCHEMBL6207099 0.74 PPARG (0.43) SLC22A12DRD2HTR1DDRD3MEN1
Iodide SCHEMBL7773907 0.73 PPARG (0.42) SLC22A12DRD2HTR1DDRD3MEN1
SCHEMBL19948194 0.72 DRD2 (0.41) DRD2HTR1DDRD3MEN1KMT2A
SCHEMBL3082218 0.72 MRGPRX4 (0.46) DRD2HTR1DDRD3MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020042541-A1 Process for producing bis( trifluoromethyl)benzaldehyde CENTRAL GLASS COMPANY, LIMITED (JP) 2002-04-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020042541-A1 Process for producing bis( trifluoromethyl)benzaldehyde BRPF1, PFAS, FLI1 SLC22A12 3842/4885DRD2 2483/4885HTR1D 2557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.