Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600674 | 0.91 | TRPM8 (0.46) | HTR2AHRH1ALOX5TRPM8KDM4E | |
| Hydrochloric Acid SCHEMBL7594995 | 0.90 | TRPM8 (0.45) | HTR2AHRH1ALOX5TRPM8KDM4E | |
| SCHEMBL7596331 | 0.85 | TRPM8 (0.41) | HTR2AHRH1ALOX5TRPM8KDM4E | |
| Hydrochloric Acid SCHEMBL7600878 | 0.84 | TRPM8 (0.41) | HTR2AHRH1ALOX5TRPM8 | |
| Hydrochloric Acid SCHEMBL7600663 | 0.84 | TRPM8 (0.41) | HTR2AHRH1ALOX5TRPM8MAPT | |
| SCHEMBL7596315 | 0.84 | MEN1 (0.42) | HTR2AHRH1ALOX5TRPM8MEN1 | |
| SCHEMBL7600460 | 0.84 | MEN1 (0.42) | HTR2AHRH1ALOX5TRPM8MEN1 | |
| Hydrochloric Acid SCHEMBL7600447 | 0.82 | ALOX5 (0.42) | ALOX5TRPM8 | |
| SCHEMBL7597931 | 0.82 | ALDH1A1 (0.44) | ALOX5TRPM8GAAKMT2A | |
| SCHEMBL7595296 | 0.82 | ALDH1A1 (0.44) | ALOX5TRPM8GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |