Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 5/20 | 0.35 |
| ▸ | BAZ2A | Q9UIF9 | 4/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.35 |
| ▸ | CTSG | P08311 | 3/20 | 0.35 |
| ▸ | KLK7 | P49862 | 3/20 | 0.35 |
| ▸ | KLK14 | Q9P0G3 | 3/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108266 | 0.66 | PTGS2 (0.45) | PTGS2 | |
| SCHEMBL13532126 | 0.63 | CYP3A4 (0.56) | PTGS2KDM4EMAPTHSD17B10ALOX15 | |
| SCHEMBL13532131 | 0.63 | ESR1 (0.41) | ALDH1A1KDM4EMAPTHIF1AHSD17B10 | |
| SCHEMBL17922579 | 0.61 | HSD11B1 (0.47) | BAZ2BBAZ2ABRD9PTGS2ALDH1A1 | |
| SCHEMBL8477421 | 0.58 | KMT2A (0.45) | BAZ2BBAZ2ABRD9CTSGKLK7 | |
| SCHEMBL6820364 | 0.58 | CA2 (0.50) | BAZ2BBAZ2ABRD9ALDH1A1KDM4E | |
| SCHEMBL3019386 | 0.58 | HSD11B1 (0.44) | BAZ2BBAZ2ABRD9CTSGKLK7 | |
| SCHEMBL7097918 | 0.57 | BAZ2B (0.46) | BAZ2BBAZ2ABRD9ALDH1A1MAPT | |
| SCHEMBL18618313 | 0.57 | HSD11B1 (0.48) | BAZ2BBAZ2ABRD9ALDH1A1KDM4E | |
| SCHEMBL29588550 | 0.57 | HSD11B1 (0.48) | BAZ2BBAZ2ABRD9ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465509-B2 | FOR THERAPY AND PROPHYLAXIS OF INFLAMMATORY DISEASE SUSCEPTIBLE TO TREATMENT WITH A NON-STEROIDAL ANTI-INFLAMMATORY AGENT | MERCK FROSST CANADA & CO. (CA) | 2002-10-15 | — | — | US | disclosed |
| US-20020058690-A1 | For therapy and prophylaxis of inflammatory disease susceptible to treatment with a non- steroidal anti-inflammatory agent | MERCK FROSST CANADA LTD. (CA) | 2002-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058690-A1 | For therapy and prophylaxis of inflammatory disease susceptible to treatment with a non- steroidal anti-inflammatory agent | PTGS1, PTGES2, PTGS2 | BAZ2B 4565/4885BAZ2A 4319/4885BRD9 4718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.