Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606033 | 0.88 | CASP1 (0.37) | MMP1MMP13 | |
| SCHEMBL7701291 | 0.78 | GFER (0.41) | MAPTALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL7690197 | 0.72 | CAPN1 (0.51) | CAPN1ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL7697381 | 0.71 | CAPN1 (0.50) | CAPN1ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL7697236 | 0.70 | CAPN1 (0.51) | CAPN1ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL7675029 | 0.68 | L3MBTL1 (0.44) | MAPTALDH1A1LMNAKMT2APOLB | |
| SCHEMBL7697613 | 0.67 | CAPN1 (0.52) | CAPN1ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL7694145 | 0.67 | CAPN1 (0.49) | CAPN1ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL7691261 | 0.66 | CAPN1 (0.47) | CAPN1ALDH1A1LMNAKMT2ABCL2 | |
| SCHEMBL7697278 | 0.65 | CAPN1 (0.47) | CAPN1ALDH1A1LMNAKMT2ABCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073632-A1 | SUBSTITUTED BENZAMIDES, THEIR PRODUCTION AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054293-A1 | SUBSTITUTED BENZAMIDES, THEIR PRODUCTION AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-28 | — | — | WO | disclosed |