Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599622 | 0.88 | CAPN1 (0.33) | MMP1MMP13 | |
| SCHEMBL7675029 | 0.78 | L3MBTL1 (0.44) | CASP1RAB9AADAMTS4MMP1MMP2 | |
| SCHEMBL7701336 | 0.73 | CASP1 (0.49) | CASP1KCNA5ADAMTS4MMP1MMP2 | |
| SCHEMBL7428250 | 0.72 | KCNA5 (0.44) | CASP1KCNA5CTSKMMP1MMP2 | |
| SCHEMBL7564537 | 0.71 | CA2 (0.54) | CASP1CA12CA1CA9RAB9A | |
| SCHEMBL7422050 | 0.70 | KCNA5 (0.49) | KCNA5MMP1MMP13CTSS | |
| SCHEMBL7421842 | 0.69 | L3MBTL1 (0.46) | RAB9A | |
| SCHEMBL7701291 | 0.69 | GFER (0.41) | CASP1CTSKRAB9AADAMTS4MMP1 | |
| SCHEMBL7695233 | 0.68 | CAPN1 (0.54) | CASP1KCNA5CTSKMMP1MMP2 | |
| SCHEMBL7703759 | 0.67 | CASP1 (0.41) | CASP1KCNA5RAB9AMMP1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073632-A1 | SUBSTITUTED BENZAMIDES, THEIR PRODUCTION AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054293-A1 | SUBSTITUTED BENZAMIDES, THEIR PRODUCTION AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-28 | — | — | WO | disclosed |