Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | KYNU | Q16719 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600399 | 0.86 | HSD17B10 (0.40) | F10PRSS1F2KYNUGPR88 | |
| SCHEMBL7599734 | 0.85 | HSD17B10 (0.39) | KYNUCYP3A4ALDH1A1ALOX15 | |
| SCHEMBL7598917 | 0.84 | HSD17B10 (0.37) | F10PRSS1F2GPR88 | |
| SCHEMBL7598928 | 0.79 | HSD17B10 (0.47) | CYP3A4 | |
| SCHEMBL8639837 | 0.77 | GPR88 (0.37) | F10PRSS1F2GPR88HPGDS | |
| SCHEMBL7596669 | 0.74 | KYNU (0.45) | KYNUALDH1A1ALOX15 | |
| SCHEMBL7600401 | 0.71 | HSD17B10 (0.51) | — | |
| SCHEMBL7598876 | 0.70 | ACE2 (0.44) | — | |
| SCHEMBL7598920 | 0.69 | HSD17B10 (0.49) | KYNU | |
| SCHEMBL8752163 | 0.68 | GPR88 (0.37) | F10PRSS1F2RAB9AGPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832085-B1 | PHOSPHINIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 2002-12-18 | — | — | EP | disclosed |