SCHEMBL7600121

SCHEMBL7600121

CN(Cc1ccc(S(C)(=O)=O)c(S(N)(=O)=O)c1)S(C)(=O)=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.40
KDM4E B2RXH2 1/20 0.37
CYP1A2 P05177 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ALDH1A1 P00352 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
CA1 P00915 3/20 0.33
CA9 Q16790 3/20 0.33
CA7 P43166 1/20 0.33
DRD2 P14416 1/20 0.33
DRD1 P21728 1/20 0.33
ACLY P53396 1/20 0.33
CA12 O43570 2/20 0.33
CA4 P22748 2/20 0.33
F10 P00742 1/20 0.33
GRIA2 P42262 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
PDIA6 Q15084 1/20 0.33
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7598754 0.80 LMNA (0.35) KDM4ECYP1A2HSD17B10ALDH1A1ACLY
SCHEMBL30925081 0.79 CA2 (0.35) CA2KDM4EALDH1A1L3MBTL1CA1
SCHEMBL28732665 0.71 CA2 (0.47) CA2KDM4EALDH1A1L3MBTL1CA1
SCHEMBL4351827 0.71 MAPT (0.43) CA2KDM4ECYP1A2HSD17B10ALDH1A1
SCHEMBL2525103 0.70 ACLY (0.39) KDM4ECYP1A2HSD17B10ALDH1A1DRD2
SCHEMBL30925088 0.70 CA2 (0.38) CA2KDM4ECYP1A2ALDH1A1L3MBTL1
SCHEMBL30925084 0.70 CA2 (0.38) CA2KDM4ECYP1A2ALDH1A1L3MBTL1
SCHEMBL5913718 0.69 CA2 (0.43) CA2ALDH1A1L3MBTL1SLC6A2SLC6A4
SCHEMBL22015598 0.69 CA2 (0.50) CA2KDM4EALDH1A1L3MBTL1CA1
SCHEMBL17560581 0.69 HSD11B1 (0.45) CA2KDM4ECYP1A2HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0900023-B1 SUBSTITUTED AMINOMETHYL PHENYL SULPHONYL UREAS, THEIR PRODUCTION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS BAYER CROPSCIENCE GMBH (DE) 2002-11-27 EP disclosed
US-5925596-A PRE-EMERGENCE AND POST-EMERGENCE HERBICIDES HOECHST-SCHERING AGREVO GMBH (DE) 1999-07-20 US disclosed
EP-0900023-A1 SUBSTITUTED AMINOMETHYL PHENYL SULPHONYL UREAS, THEIR PRODUCTION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS Hoechst Schering AgrEvo GmbH (DE) 1999-03-10 EP disclosed
WO-1997040690-A1 SUBSTITUTED AMINOMETHYL PHENYL SULPHONYL UREAS, THEIR PRODUCTION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1997-11-06 WO disclosed